This is a disorder that usually only occurs among uplifted octopi. It is a form of anxiety disorder characterized by self-cannibalism of the limbs. Subjects afflicted with autophagy will, under stress, begin to consume their limbs, if at all possible, causing themselves potentially serious harm.

Anytime an uplifted octopi with this disorder is placed in a stressful situation they must make a successful WIL x 3 Test or begin to consume one of their limbs.